You are currently browsing the archives for the intrinsic and innate immunity category.

How does your body ‘know’ it’s been infected?

Published on: Author: the CVR science blog editors

Join Andrew Shaw and Connor Bamford – CVR postdocs – for a chat with Professor Jan Rehwinkel from the University of Oxford and MRC Human immunology unit in this recent episode of Contagious Thinking. Following Jan’s recent seminar at the CVR, he talks with the podcast about his lab’s work on understanding how our cells… Continue reading

Steve Goodbourn ….and a world full of chickens and their viruses

 Professor Steve Goodbourn, from St George’s, University of London, talks with PhD students Joanna Morrell and Yasmin Parr about his his work on unravelling the biochemical mysteries of how viruses unravel the innate immune system of their hosts. Steve’s work has been integral to our understanding of how some of the most dangerous viruses can infect… Continue reading

Innate Immunity: Slippery when wet

Published on: Author: the CVR science blog editors

Dr Jens Madsen, Associate Professor in Child Health at the University of Southampton, talks with PhD students Yasmin Parr and Joanna Morrell for episode 8 of Contagious Thinking and tells us all about the mucosal surfactant proteins, the Collectins, that form a crucial innate immune barrier against viruses and other microbes. Jens and his lab… Continue reading

What do you mean by ‘infectivity’? A conversation with Richard Hardy

Published on: Author: the CVR science blog editors

  Is the ebolavirus mutating to become more transmissible in humans? Why was Zika virus able to move across the world so rapidly? Why are some viruses able to spread via aerosols floating in the air? While these may all appear to be very distinct questions, there is one major factor that connects them: the concept… Continue reading

The CVR at Glasgow Science Festival 2016: exploring biological structure and innovation through viruses

Published on: Author: the CVR science blog editors

In a world obsessed with the deadly nature of viruses, join us in a celebration of the beauty of their biological structure. Glasgow is a fascinating place to live, with awesome architecture and design emerging from the dramatic Scottish landscape. Although invisibly small, viruses also produce strikingly beautiful structures, constructed from the local materials of… Continue reading

Human cells can ADAP2 inhibit virus entry

Published on: Author: the CVR science blog editors

Knowledge of how cells and organisms defend themselves against pathogenic microbes is of paramount interest in our understanding of infection and immunity. Determining the mechanism by which cells achieve this – and exploiting this knowledge – may aid in the development of therapies as well as improving our understanding of how these microbes cause disease. Shu et al., (from the… Continue reading

Arbovirus vectors: a view to a kill

Published on: Author: the CVR science blog editors

As the International Meeting on Arboviruses and their Vectors, kicks off today in Glasgow with the Society for General Microbiology (#IMAV15),  we’d like to present to you the fifth and final in a series of posts about arboviruses, their vertebrate hosts and their arthropod vectors. This post, written by Dr Alain Kohl ,CVR Arthropod-borne infections programme leader along with… Continue reading

The yin and yang of being an arbovirus host

Published on: Author: the CVR science blog editors

“While arboviruses do not generally cause recognisable disease in their arthropod vectors they often do in vertebrates, in particular warm-blooded vertebrates like primates like us and livestock. “ As classically defined, arboviruses have both arthropod and non-arthropod hosts. Whilst insects/ticks may have legs, jaws and eyes etc., they are clearly very different to their vertebrate hosts, such as… Continue reading